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Fakultät BCI

Dr. Ramona Strob


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Department of Biochemical and Chemical Engineering
Laboratory of Solids Process Engineering
Emil-Figge-Str. 68
44227 Dortmund



One of the major problems for the development of new drug substances is the poor aqueous solubility. The preparation of submicron sized particles (0.1-1µm) can increase the dissolution rate as well as the solubility of the drugs, thus increases their bioavailability. In this work spray drying is used for the generation of submicron sized particles.


Spray Drying is as a gentle, continuous and single-step technique, widely used in the pharmaceutical application, which converts a fluid into a dry powder.

Nevertheless, the production of particles at the submicrometer range using conventional spray dryers is limited due to the low collection efficiency (< 2 µm) of cyclone separator, the low yield and due to insufficient forces of atomization to produce small droplets.[1]

The aim of this research is the production of submicron particles using spray drying technique. Therefore the identification of a new robust atomization technique generating small droplet sizes and a narrow droplet size distribution is from common interest.


  1. Sosnik, A., Seremeta, K., Adv. Colloid. Interface Sci. , 223, 40-54, 2015

Curriculum Vitae

Since 2015 PhD at the Laboratory of Solids Process Engineering, TU Dortmund
2013 - 2014

M.Sc. Biochemical Engineering, TU Dortmund
Master thesis: Development, construction and characterization of a continuously operated tubular crystallizer

2009 - 2013

B.Sc. Biochemical Engineering, TU Dortmund
Bachelor thesis: Determination of the thermal conductivity of crystalline organic compounds

2000 - 2009 Galilei-Gymnasium (Hamm Westf.)
Born November 26th, Hamm Westf. (Germany)