Dr. Adrian Dobrowolski

Contents

Abstract

The bioavailability enhancement of poorly water soluble drugs can be achieved by the decrease of the particle size of active pharmaceutical ingredients. An innovative process is the spray drying with spray conditioning to produce submicron particles. A resulting challenge is the collection of these dispersed particles from a gas flow. This work examines the deposition of submicron particles in an electrostatic precipitator (ESP).
 

Description

The separation in ESP is a common technique for air purification purposes where powder particles can be collected rather independently from particle size. An adapted ESP design is necessary to achieve high separation efficiencies and a robust process.

The ESP design in this work uses the precipitation method of Penney filters which separates charging and collection into two zones.

The aim of this research is the improvement of the precipitation efficiency of submicron particles using ESP.

Curriculum Vitae